Research and clinical data supporting the therapeutic use of nutrients for schizophrenia includes:Hoffer's original double blinds introducing nutritional psychiatry
Dr. Abram Hoffer, MD, PhD, introduced double blinds to psychiatric research with his early niacin studies in the sixties. But, as a physician pledged to do no harm, he eventually decided not to deprive controls (patients) of treatments which he had observed to work, so as not to place them at risk of permanent deterioration, or death.
Hoffer's clinical results with 10,000 schizophrenic patients
Over the next half century, Hoffer practiced orthomolecular psychiatry, eventually treating 10,000 schizophrenic patients, most of whom recovered to a degree not expected with conventional treatments.